COVID-19

Hidroxicloroquina e Azitromicina

  1. Gautret P, Lagier JC, Parola P, et al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial [published online ahead of print, 2020 Mar 20]. Int J Antimicrob Agents. 2020;105949. doi:10.1016/j.ijantimicag.2020.105949.

    Esse foi o estudo francês responsável por causar todo o agitamento na ciência em busca de um remédio milagroso para curar a COVID-19.

    Hidroxicloroquina: o dia em que a ciência parou: postagem no blog Medicina Baseada em Evidências criticando a interpretação apressada do estudo acima.

  2. Sahraei Z, Shabani M, Shokouhi S, Saffaei A. Aminoquinolines Against Coronavirus Disease 2019 (COVID-19): Chloroquine or Hydroxychloroquine [published online ahead of print, 2020 Mar 16]. Int J Antimicrob Agents. 2020;105945. doi:10.1016/j.ijantimicag.2020.105945.

  3. Guo YR, Cao QD, Hong ZS, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status. Mil Med Res. 2020;7(1):11. Published 2020 Mar 13. doi:10.1186/s40779-020-00240-0.

  4. Cheng, V. C., Lau, S. K., Woo, P. C., & Yuen, K. Y. (2007). Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection. Clinical microbiology reviews, 20(4), 660-694. https://doi.org10.1128/CMR.00023-07.

  5. Menachery, V. D., Yount Jr, B. L., Debbink, K., Agnihothram, S., Gralinski, L. E., Plante, J. A., … & Randell, S. H. (2015). A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nature medicine, 21(12), 1508. https://doi.org/10.1038/nm.3985.

  6. Liu Y, Gayle AA, Wilder-Smith A, Rocklöv J. The reproductive number of COVID-19 is higher compared to SARS coronavirus. J Travel Med. 2020;(February):1–6.

  7. Muniz-Rodriguez K, Chowell G, Cheung C-H, Jia D, Lai P-Y, Lee Y, et al. Epidemic doubling time of the COVID-19 epidemic by Chinese province. medRxiv Prepr. 2020;

  8. Wang C, Liu L, Hao X, Guo H, Wang Q, Huang J, et al. Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of Coronavirus Disease 2019 in Wuhan, China. medRxiv. 2020;

  9. Fan, Y.; Zhao, K.; Shi, Z.-L.; Zhou, P. Bat Coronaviruses in China. Viruses 2019, 11, 210.

  10. Grein J, Ohmagari N, Shin D, et al. Compassionate use of remdesivir for patients with severe covid-19. N Engl J Med. April 2020:NEJMoa2007016. doi:10.1056/NEJMoa2007016.

Distanciamento social

  1. Kissler SM, Tedijanto C, Goldstein E, Grad YH, Lipsitch M. Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period [published online ahead of print, 2020 Apr 14]. Science. 2020;eabb5793. doi:10.1126/science.abb5793.

    O estudo que projetou distanciamento social até 2022 por causa da COVID-19: minha postagem comentando esse estudo.

BCG

  1. Miller A, Reandelar MJ, Fasciglione K, Roumenova V, Li Y, Otazu GH. Correlation between Universal BCG Vaccination Policy and Reduced Morbidity and Mortality for COVID-19: An Epidemiological Study. Epidemiology; 2020. Preprint medRxiv 2020.03.24.20042937; doi:10.1101/2020.03.24.20042937.

    Universal BCG vaccination and protection against COVID-19: critique of an ecological study: postagem no blog da Nature criticando esse estudo.

Gestantes

  1. Alzamora MC, Paredes T, Caceres D, Webb CM, Valdez LM, La Rosa M. Severe COVID-19 during Pregnancy and Possible Vertical Transmission [published online ahead of print, 2020 Apr 18]. Am J Perinatol. 2020;10.1055/s-0040-1710050. doi:10.1055/s-0040-1710050.

    Relato de caso sobre uma evolução grave da COVID-19 em gestante que necessitou ser intubada e realizar cesárea de emergência. O neonato, mesmo sendo isolado do contato, apresentou swab nasal e RT-PCR positivos para o SARS-CoV-2. Possibilidade de transmissão vertical intra-útero?